Verified Nov 2026
Batteries & E-Mobility
·
Hopkinton, Massachusetts
·
Since 1997
Isto Biologics is a regenerative medtech company headquartered in Hopkinton, Massachusetts, founded in 1997 and employing roughly 100 to 200 people, with estimated revenue of $50 to 100 million. It is privately held, with Keensight Capital having acquired a majority stake in September 2025. The company makes orthobiologic and cell-therapy products, including bone graft substitutes and autologous platelet separation systems, for spine, orthopedic, and sports medicine applications. In August 2026, it announced the acquisition of NovaBone to strengthen its bone graft substitutes platform.
Isto Biologics at a glance
Revenue
$50-100M
Est. band
Employees
100-200
Founded
1997
Headquarters
Hopkinton, Massachusetts
Industries
Automotive
Electric Vehicles
Medical
Industrial Equipment
Overview
Isto Biologics is a regenerative medtech company headquartered in Hopkinton, Massachusetts, founded in 1997 and employing roughly 100 to 200 people, with estimated revenue of $50 to 100 million. It is privately held, with Keensight Capital having acquired a majority stake in September 2025. The company makes orthobiologic and cell-therapy products, including bone graft substitutes and autologous platelet separation systems, for spine, orthopedic, and sports medicine applications. In August 2026, it announced the acquisition of NovaBone to strengthen its bone graft substitutes platform.
At a glance
Attribute | Detail |
|---|---|
Founded | 1997 |
Headquarters | Hopkinton, Massachusetts |
Employees | 100-200 |
Revenue | $50-100M (estimated) |
Primary capability | Batteries & E-Mobility |
What Isto Biologics makes
The company's product lines, as listed on its website, span orthobiologic and cell-therapy offerings used in orthopedic, spinal, and bone-regeneration procedures, though no certifications are recorded in the directory.
Products and capabilities described on the company's own site include Glass, LED (source: istobiologics.com).
Latest developments
2026-08-06 — Hopkinton’s Isto Biologics acquires Florida bonehealing firm for $60M (wbjournal.com)
2026-08-04 — Isto Biologics strengthens its bone graft substitutes platform with the acquisition of NovaBone (istobiologics.com)
2026-04-01 — Adaptive Re-use Transformation for Isto Biologics: Demolition to Completion | Integrated Builders (integratedbuilders.com)
2025-10-02 — Isto Biologics Announces New Leadership Transition (istobiologics.com)
2025-09-17 — Keensight Capital acquires majority stake in Isto Biologics, a leading orthobiologics player, from Thompson Street Capital Partners (istobiologics.com)
2025-09-17 — Keensight Buys Majority Stake in Isto in $1 Billion Deal - Bloomberg (bloomberg.com)
Facilities
Isto Biologics is headquartered in Hopkinton, Massachusetts. Public sources also reference these locations:
Alachua, Florida — istobiologics.com
Company details
Isto Biologics is privately owned, with Keensight Capital holding a majority stake, and it serves the automotive, electric-vehicle, medical, and industrial-equipment sectors according to its industry classification. Isto Biologics was founded in 1997, has an estimated 100-200 employees, and is headquartered in Hopkinton, Massachusetts.
Frequently asked questions
What does Isto Biologics make?
Isto Biologics is a regenerative medtech company headquartered in Hopkinton, Massachusetts, founded in 1997 and employing roughly 100 to 200 people, with estimated revenue of $50 to 100 million. It is privately held, with Keensight Capital having acquired a majority stake in September 2025. The company makes orthobiologic and cell-therapy products, including bone graft substitutes and autologous platelet separation systems, for spine, orthopedic, and sports medicine applications. In August 2026, it announced the acquisition of NovaBone to strengthen its bone graft substitutes platform.
Where is Isto Biologics headquartered?
Isto Biologics is headquartered in Hopkinton, Massachusetts (45 South Street, Hopkinton, Massachusetts, 01748).
When was Isto Biologics founded?
Isto Biologics was founded in 1997.
How big is Isto Biologics?
Isto Biologics has an estimated 100-200 employees, with revenue in the $50-100M range (estimated).
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Last verified Nov 2026. Is this your company? Request a correction.
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